Postdoctoral fellow, graduate student and research assistant positions are available for highly motivated trainees in biomedical science.
The laboratory studies the genetic determinants of blood cell development, homeostasis, and disease. We develop and employ genome editing methodologies to perturb and observe blood cells. We have identified an erythroid enhancer of BCL11A as a favorable target for therapeutic gene editing in β-hemoglobin disorders. We are committed to advancing first-in-human gene editing investigations. Our studies are meant to elucidate fundamental mechanisms of gene regulatory elements in their endogenous chromosomal environment and develop innovative treatment strategies for blood disorders.
Prior experience in protein engineering, gene editing and gene therapy, molecular and cell biology, genetics, biochemistry, hematopoiesis, systems biology, structural/chemical biology, and/or computational biology/bioinformatics is highly desirable. The candidate must be independent in scientific research and writing, self-motivated, ethical, team spirited, and must have exceptional laboratory, communication, organizational, and writing skills.
Please send a cover letter, CV, statement of research interest and contact information for three references via email to Daniel Bauer, MD PhD (bauer@bloodgroup.tch.harvard.edu), Division of Hematology/Oncology, Department of Pediatrics, Boston Children’s Hospital, Harvard Medical School, Boston, MA.
Boston Children’s Hospital is one of the top pediatric research centers in the world, and a major research and teaching affiliate of Harvard Medical School.